Core Services

The Spatial and Genome Technologies Core offers Xenium, 10x Genomics’ high-resolution spatial transcriptomics platform for single-molecule RNA detection in intact tissues. Xenium enables subcellular spatial mapping of hundreds of genes simultaneously, unlocking powerful insights into tissue architecture, cell-cell interactions and gene expression dynamics. We provide full-service support for Xenium projects, including:

• Guidance on panel selection (human and mouse available)
• Tissue sectioning and optional histology (in collaboration with the Research Histology Core)
• Xenium assay execution and high-resolution imaging
• Data processing, quality control and spatial analysis support

Ideal for both discovery and hypothesis-driven research, Xenium brings spatial context to your transcriptomic data with unparalleled precision.

Interested in exploring Xenium for your research? Contact us for a consultation or project planning session.

The Spatial and Genome Technologies Core offers Visium, the powerful spatial transcriptomics platform from 10x Genomics that maps whole-transcriptome gene expression to intact tissue sections. Visium enables researchers to visualize and quantify gene activity in the spatial context of tissue architecture—bridging histology and transcriptomics.

We support both fresh frozen and FFPE (with CytAssist) workflows for a wide range of species, including human, mouse and custom model organisms. Our Visium services include:

• Tissue preparation, sectioning and H&E staining (in collaboration with the Research Histology Core)
• Imaging and spatial alignment (in collaboration with the Research Histology Core)
• Visium assay execution and library prep
• Sequencing coordination and data analysis support
• Guidance on custom or species-specific panel design

Bring spatial context to your gene expression studies. Contact us to get started with Visium.

The Spatial and Genome Technologies Core offers a full suite of Chromium Single Cell technologies from 10x Genomics, enabling high-throughput, high-resolution analysis of individual cells from complex tissues or heterogeneous samples. Whether you’re studying gene expression, immune profiling or multi-omics, Chromium assays provide deep insight into cellular diversity and function. We support a range of Chromium applications, including:

• Single Cell Gene Expression (scRNAseq)
• Single Cell Immune Profiling (TCR/BCR sequencing)
• Single Cell ATAC-seq for chromatin accessibility
• Multiome (Gene Expression + ATAC)
• Cell surface protein expression
• Intracellular protein expression

Our services include:

• Sample QC and consultation
• Assay execution
• Library preparation and sequencing coordination
• Data processing and preliminary analysis support

Unlock cellular-level resolution in your research. Reach out to discuss your project and sample requirements.